(1) Other potential causes of peripheral neuropathy were excluded before attributing the peripheral neuropathy to diabetes.(2) In other words, aspartame disease can simulate diabetic retinopathy or peripheral neuropathy .(3) If diabetic neuropathy has damaged the nerves in your legs and feet, you may not be able to feel pain in those parts of your body.(4) Assessing the lower limbs for peripheral neuropathy and vascular disease also is important.(5) This includes assessment of infection, neuropathy and peripheral vascular disease.(6) The spasms of multiple sclerosis and resistant neuropathic pain are two obvious targets.(7) Margolis and colleagues developed a clinical prediction model that can determine which diabetic neuropathic foot ulcers will respond to standard therapy in a reasonable amount of time.(8) The commonest cause of neuropathic ulceration is diabetes, and many diabetic patients with neuropathic ulceration will also have an arterial problem that requires correction.(9) In fact, we owe much of what we know about managing neuropathic foot ulcerations related to diabetes to Dr Brand's pioneering work.(10) About 86 percent of those with multiple sclerosis suffer from neuropathic pain, or nerve pain, a common symptom of the disease.