(1) Preoperatively, radiation is delivered to decrease the risk of local recurrence, prevent the development of distant metastasis and reduce tumor size to permit sphincter-preserving surgery.(2) A malignant neoplasm in the neck can arise as a primary tumor or as metastasis from the upper aerodigestive tract or a distant site.(3) Sixteen cervical lymph nodes with metastasis of oral cancer and 20 benign lymph nodes were studied.(4) However, only in 3 of these cases was the morphologic appearance in the metastasis so well differentiated as to be considered benign if taken out of context.(5) This eliminates perverse growth, anticipating the metastasis that is seeking to re-enter the system.(6) Six years later, a fine-needle aspirate of a cervical vertebra showed malignant cells consistent with metastasis from a primary lung carcinoma.(7) GTP inhibited the levels of urokinase plasminogen activator as well as matrix metalloproteinases 2 and 9, cellular molecules linked to the metastasis .(8) an increased risk of metastasis(9) Patients with a diagnosis of granular cell tumor should have a complete physical examination to exclude other primary tumors or metastasis from an aggressive malignant tumor.(10) Breast tumors may also be the result of metastasis from primary prostate cancer.(11) The purpose of this study was to investigate in detail the pathologic aspects of thyroid cancers with bone metastasis and to compare these with various clinical parameters.(12) Bisphosphonates reduce skeletal morbidity in cancer patients with metastatic bone disease.(13) Meningeal spread is not uncommon in cases of intracranial gliomas or metastatic carcinoma.(14) Among the neoplastic lesions, both primary and metastatic malignancies must be considered.(15) The echocardiography and the pathologic examination revealed a metastatic melanoma.(16) Unlike carcinomas, metastatic sarcomas generally occur deeper and may not ulcerate the mucosa.
