(1) Occasionally, the upper reticular dermis also may be infiltrated, but by isolated single cells.(2) The epidermis is devoid of blood vessels but is nourished by diffusion from capillaries in the underlying dermis .(3) The reactive epithelium may extend into the superficial reticular dermis , simulating a carcinoma.(4) Mitotic figures are variably present, and tumor aggregates may extend into the reticular dermis or even subcutaneous fat.(5) The biopsy should include surrounding skin with underlying dermis and connective tissue so that the pathologist can evaluate the depth of stromal invasion.(6) The thicker or inner layer of the dermis contains blood vessels, hair follicles, nerve endings, sweat and sebaceous glands.(7) The dermal-epidermal junction, papillary dermis, and reticular dermis were assessed separately.(8) Although it is composed of two primary layers, the outer epidermis and the inner dermis , it also contains arteries, veins, nerve fibers, sweat glands and hair follicles among other things.(9) Cigarettes independently damage the elastic fibers of the dermis and promote elastosis similar to that found in sun-exposed skin.(10) The middle layer, or dermis , contains connective tissue, small blood vessels, sweat and oil glands, nerves, and cells that produce collagen, called fibroblasts.(11) While the dermal layer has many capillaries, it has fewer nerve endings at sites other than the fingers.(12) The latter, less numerous than the dermic receptors, were situated among the keratinocytes as far as the most superficial strata.(13) In normal tissue, the color returns swiftly as the blood refills the dermal capillaries.(14) The tumor typically presents as a painless dermal or subcutaneous mass, which slowly grows for a period of months or years.(15) A new biopsy showed the persistence of the dermic infiltration, compatible with ‘T’ cutaneous lymphoma.(16) The blood is fixed within damaged capillaries in the deep dermal plexus
